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ea0022p545 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Prothrombin time, activated thromboplastin time, fibrinogen, and D-dimer levels, and von Willebrand activity of patients with Sheehan's syndrome and the effect of hormone replacement therapy

Pasa Semir , Altintas Abdullah , Tumer Cemil , Demircin Mstafa

Increased mortality due to atherosclerotic cardiovascular disease has been described in adult patients with hypopituitarism, although the precise underlying mechanisms remain undetermined. Various abnormalities of coagulation and fibrinolysis occur in patients with thyroid diseases. Conversely, there are conflicting reports concerning the effects of growth hormone replacement on coagulation and fibrinolytic pathways in adults with hypopituitarism, and there are limited data on...

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ea0014p613 | (1) | ECE2007

Effect of hormone replacement therapy apart from growth hormone on the endothelial functions in patients with Sheehan’s syndrome

Bahceci Mithat , Pasa Semir , Akay Hatice O , Tuzcu Alpaslan , Arikan Senay , Gokalp Deniz

Aim: To examine the endothelial functions of patients with Sheehan syndrome (SS) and to eveluate the effects of hormone replacement treatment except growth hormone on endothelial functions.Subjects and methods: Twenty-four patients with Sheehan syndrome (PSS) aged 40.83±6.43 yr and 25 healthy control women aged 41.13±6.51 yr (C) were included. Endothelial functions were evaluated with high resolution ultrasonography (flow mediated dilatation:FM...

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Endocrine Abstracts

Prothrombin time, activated thromboplastin time, fibrinogen, and D-dimer levels, and von Willebrand activity of patients with Sheehan's syndrome and the effect of hormone replacement therapy

Effect of hormone replacement therapy apart from growth hormone on the endothelial functions in patients with Sheehan’s syndrome

BiosciAbstracts